Bryan County is a county in the U.S. state of Oklahoma. As of the 2020 census, the population was 46,067. Its county seat is Durant. It is the only county in the United States named for Democratic politician William Jennings Bryan. Bryan County comprises the Durant, OK micropolitan statistical area, which is part of the Dallas-Fort Worth and the Texoma region, TX-OK combined statistical area. The city of Durant has the headquarters of the Choctaw Nation of Oklahoma.