Iona is an unincorporated community and census-designated place in Lee County, Florida, United States. The population was 16,908 at the 2020 census, up from 15,404 at the 2010 census. It is part of the Cape Coral-Fort Myers, Florida Metropolitan Statistical Area. A strong EF2 tornado struck the town on January 16, 2022, causing major damage and injuring three people.