Hico is a census-designated place in Fayette County, West Virginia, United States. Hico is located at the junction of U.S. routes 19 and 60, 7 miles northeast of Fayetteville. Hico has a post office with ZIP code 25854. As of the 2010 census, its population was 272. Some say the community was named after a variety of tobacco called hico, while others believe the name is a transfer from Hyco, Virginia. On April 2, 2024; an EF2 tornado caused significant damage just to the south of Hico.