Hespeler is a neighbourhood and former town within Cambridge, Ontario, located along the Speed River in the Regional Municipality of Waterloo, Ontario, Canada. In 1973, Hespeler, Preston, Galt, and the hamlet of Blair were amalgamated to form the City of Cambridge. The first mayor of Cambridge was Claudette Millar. No population data is available for the former Hespeler since the census reports cover only the full area of Cambridge.