Belpre is a city in Washington County, Ohio, United States, along the Ohio River. The name Belpre is derived from a contraction of "Belle Prairie" (French for "beautiful meadow"), which is the original name given to the valley by French trappers prior to more permanent settlement by European Americans. Part of the Parkersburg-Marietta-Vienna, WV-OH Metropolitan Statistical Area, the city is located about 14 miles downriver from Marietta.