Desenzano del Garda-Sirmione railway station serves the town and comune of Desenzano del Garda, in the region of Lombardy, northern Italy. Opened in 1854, it forms part of the Milan–Venice railway. The station is currently managed by Rete Ferroviaria Italiana (RFI). However, the commercial area of the passenger building is managed by Centostazioni. Each of these companies is a subsidiary of Ferrovie dello Stato (FS), Italy's state-owned rail company.