Tyrone is a borough in Blair County, Pennsylvania, United States, located 15 miles northeast of Altoona, on the Little Juniata River. Tyrone was of considerable commercial importance in the twentieth century. It was an outlet for the Clearfield coal fields and was noted for manufacturing paper products. There were planing mills and chemical and candy factories. In 1900, 5,847 people lived here; in 1910, 7,176; and in 1940, 8,845 people resided here. The population was 5,477 at the 2010 census.