Dubois is a city in Clark County, Idaho, United States. The population was 511 at the 2020 census. The city is the county seat of Clark County. The city was named in 1892 for Fred Dubois, a prominent politician in Idaho's early years. He came to Idaho in 1880, later becoming the state's first U.S. Senator, serving two non-consecutive terms. Six miles north of town is the U.S. Sheep Experiment Station, the county's second largest employer.