Caseville is a city in Huron County in the U.S. state of Michigan, located at the mouth of the Pigeon River on Saginaw Bay of Lake Huron. The population was 652 at the 2020 census. The city is surrounded by Caseville Township. A popular destination for summer tourists, it sponsors the 10-day Cheeseburger in Caseville festival, a tribute to Jimmy Buffett's song "Cheeseburger in Paradise".