Indio is a city in Riverside County, California, United States, located in the Coachella Valley of Southern California's Colorado Desert region. It lies 23 miles east of Palm Springs, 77 miles east of Riverside, and 127 miles east of Los Angeles. It is about 98 miles north of Mexicali, Baja California on the U.S.-Mexican border. The word Indio is Spanish for Indian. The population was 76,036 in the 2010 United States Census, up from 49,116 at the 2000 census, an increase of 55%.