There’s something in the water here, quite literally. A key player in wellness before we even had a word for it, this hotel and spa in the heart of California wine country is all about letting your mind and body relax. It taps into the area’s underground hot springs to provide natural mineral pools in three different temperatures, alongside mud baths and a spa with treatments to spare. Once you’re thoroughly unwound, head back to your sleek, cleanly designed room or spacious cottage.