Conestee is an unincorporated community and census-designated place in Greenville County, South Carolina, United States. It was first listed as a CDP in the 2020 census with a population of 904. Conestee's main attraction is Lake Conestee Nature Park. The community is bordered by the city of Greenville to the north, Mauldin to the east and Gantt to the west. Conestee Mill and McBee Methodist Church are listed on the National Register of Historic Places and located in Conestee.