Medical City Denton, (formerly Denton Regional Medical Center) or Denton Regional, is a full-service hospital operated by Hospital Corporation of America and is located at 3535 South Interstate 35, southeast of downtown Denton, Texas. It houses 200 beds, and employs more than 850 employees and 285 physicians. Denton Regional serves patients from Denton, Wise, Cooke and Montague Counties.