Maker-with-Rame is a civil parish in Cornwall, England, United Kingdom. It is situated on the Rame Peninsula, approximately four miles south of Saltash and two miles west of Plymouth. The parish was formed in 1941 from the ecclesiastical parishes of Maker and Rame. It occupies the eastern end of the Rame peninsula and is surrounded on three sides by sea: the Hamoaze to the north, Plymouth Sound to the east, and the English Channel to the south and southwest.