Pascoe Vale South is an inner suburb in Melbourne, Victoria, Australia, 8 km north of Melbourne's Central Business District, located within the City of Merri-bek local government area. Pascoe Vale South recorded a population of 10,534 at the 2021 census. Pascoe Vale South adjoins Brunswick West to the south, Strathmore and the Moonee Ponds Creek to the west, Coburg to the east, and Pascoe Vale to the north. The suburb also borders the Tullamarine Freeway.