Parkersburg is a city in and the county seat of Wood County, West Virginia, United States. Located at the confluence of the Ohio and Little Kanawha rivers, it is the state's fourth-most populous city and the center of the Parkersburg–Vienna metropolitan area. The city's population was 29,749 at the 2020 census, and its metro population was 89,490. The city is about 14 miles south of Marietta, Ohio.