Pyin Oo Lwin District is a district of the Mandalay Region in central Myanmar. It lies northeast of Mandalay, and consists solely of Pyin Oo Lwin Township. Prior to 2022, it contained five townships with the Myitnge River as its southern boundary. To the east it is bordered by Shan State and in part by the Chaung Magyi. It goes north as far as the town of Dakaung where it adjoins Htigyaing Township, Katha District in Sagaing Region.