Murrells Inlet is an unincorporated area and census-designated place in Georgetown County, South Carolina, United States. The population was 7,547 at the 2010 census. It is about 13 miles south of Myrtle Beach, South Carolina and 21 miles north of Georgetown, the county seat. The community was once primarily a fishing village. It has developed in modern times, along with the rest of the Grand Strand, as a tourist and retirement location.