Tubutama is a town in the north-west of the Mexican state of Sonora. It serves as the seat for the surrounding municipality of the same name. The municipal area is 1,351.60 km2, and the population was 1,798 in 2005. The main economic activities are cattle raising and subsistence farming. Eusebio Kino, SJ, founded Mission San Pedro y San Pablo del Tubutama in 1691.