Kershaw County is a county located in the U.S. state of South Carolina. As of the 2020 census, its population was 65,403. The county seat and largest community is Camden. The county was created in 1791 from parts of Claremont, Lancaster, Fairfield, and Richland counties. It is named for Col. Joseph Kershaw, an early settler and American Revolutionary War patriot. Kershaw County is part of the Columbia, SC Metropolitan Statistical Area.