Perrin is a census-designated place and unincorporated community in southeastern Jack County, Texas, United States. As of the 2010 census it had a population of 398. It is located at the intersection of US Highway 281 and FM 2210. US 281 leads north from Perrin 14 miles to Jacksboro and south 16 miles to Mineral Wells. Fort Worth is 53 miles to the southeast.