Siena is a city in Tuscany, Italy. It is the capital of the province of Siena. Siena is the 12th largest city in the region by number of inhabitants, with a population of 53,062 as of 2022.The city is historically linked to commercial and banking activities, having been a major banking center until the 13th and 14th centuries. Siena is also home to the oldest bank in the world, the Monte dei Paschi bank, which has been operating continuously since 1472.