Porto Empedocle is a town and comune in Italy on the coast of the Strait of Sicily, administratively part of the province of Agrigento. It was named after Empedocles, a Greek pre-Socratic philosopher and a citizen of the city of Akragas, in his day a Greek colony in Sicily. The primary industries of Porto Empedocle are agriculture, fishing, ironworking, pharmaceuticals and rock salt refining.