Packwaukee is an unincorporated census-designated place located in the town of Packwaukee, Marquette County, Wisconsin, United States. Packwaukee is located on the north bank of Buffalo Lake, a lake on the Fox River; it is 7 miles west-southwest of Montello. Packwaukee has a post office with ZIP code 53953. As of the 2010 census, its population was 262.