Milano is a city in Milam County, Texas, United States, located at the intersection of U.S. Route 79 and State Highway 36, twelve miles southeast of Cameron, the county seat. Its population was 390 at the 2020 census. On November 5, 1960, country music singer Johnny Horton was killed by a drunk driver on Highway 79 near Milano on his way home from a performance at the Skyline Club in Austin, Texas.