Mannheim, officially the University City of Mannheim, is the second-largest city in the German state of Baden-Württemberg after the state capital of Stuttgart, and Germany's 21st-largest city, with a 2020 population of approximately 309,119 inhabitants. The city is at the centre of the Rhine-Neckar Metropolitan Region, Germany's eighth-largest metropolitan region. Mannheim is located at the confluence of the Rhine and the Neckar in the Kurpfalz region of northwestern Baden-Württemberg.