This is one of those museums which is beautiful from the inside and out. Palm Springs Art Museum is a huge collection of contemporary art, from paintings to glass and sculpture, but with a desert theme. Think Native American art, Modernism and the American West, laid out in a 10,000-square-foot auditorium, featuring everyone from Edward Curtis to Henry Moore. There are also two sister locations, one in downtown and one in Palm Desert.

The 100-ton Brontosaurus and T. Rex sculptures once beckoned motorists on their way to Palm Springs to a 24-hour diner. Today, they guard the entrance to a Creationist-themed dino museum with an interesting take on the facts. At the very least, pose for a photo with Mr. Rex and walk into the gift shop housed inside Dinny the Brontosaurus’s belly.

This air museum primarily showcases World War II and combat aircraft from the wars in Korea and Vietnam. You’ll find more than 40 flyable and static planes across three warehouses, from the B-17 flying fortress to the F-4 fighter jet, and a couple of aircraft on the tarmac, like the C-47 and PBY Catalina Flying Boat. The museum also offers a limited number of high-priced flights aboard the C-47 Skytrain and P-51 Mustang.

True to its name, this zoo looks just like a living slice of the Sonoran Desert. Located a couple of miles outside Palm Springs, the largely outdoor locale is broadly split into North American and African environments. Explore the grounds to find an assortment of wild cats and hoofed mammals. You can also feed the giraffes, which is an experience and a half.

Craggy peaks, climbable boulders, and those beloved yuccas are barely an hour car ride away. Joshua Tree National Park is a popular destination for overnight campers, but you can explore plenty in a single afternoon, from an easygoing hike around Hidden Valley to vistas from 5,000 feet up at Keys View. If you’re coming from Palm Springs, you’ll want to enter from the northwest entrance in Joshua Tree; if you’re staying farther east into the Coachella Valley, you can use the south entrance.

Though only an acre in size, this botanical garden is packed with prickly varieties of cacti and other desert plants. The family-owned garden dates back to the 1930s and harbors more than 3,000 specimens of desert plants from around the world, grouped by region. There's also a nursery if you want to take some plants back home with you—a rather lively souvenir if you ask us.

Flowing water in the middle of the desert? Indeed, this two-mile loop leads to a 50-foot waterfall tucked into Tahquitz Canyon. The falls are located within the Agua Caliente Band of the Cahuilla Indians reservation, so you’ll need to pay an admission fee. On the plus side, the fee keeps the trail impeccably maintained, unlike many of L.A.’s graffiti-filled waterfalls. Ranger-led hikes are also available.

Sunnylands, the former winter retreat for the wealthy Annenberg family and a popular summit space for decades of presidents, resides on a 200-acre plot of irrigated desert in Rancho Mirage. Though much of that space is occupied by a nine-hole golf course, 12 acres have been dedicated to public gardens and a visitor center with a rotating selection of artwork from the Annenberg collection. Tours of the mansion are available but regularly sell out months in advance.

You can barely walk a block along Palm Canyon Drive without stumbling upon an eye-catching gallery, antique, or furniture showroom. Palm Springs and mid-century modernism go hand in hand, and you’ll find plenty of galleries (notably a showroom from retro-inspired artist SHAG) and furniture stores dedicated to the jet-setting aesthetic.

Even if you don’t need any information from the official Palm Springs welcome center, this distinctive spot is worth a stop to admire its treasured architecture; the Space Age structure opened in 1965 as a gas station, but when the Albert Frey and Robson Chambers’s retro design was slated for the wrecking ball in the ’90s it was saved and turned into a visitors' center. If you do need some guidance, you can book a tour of Palm Springs.