An Italian hotel with a German name is the sort of thing that only happens in South Tyrol, the Alpine corner of Italy. That’s where you’ll find the Lake Spa Hotel Seeleiten. It’s set by the side of Lake Caldaro, in a spectacular wine-producing valley surrounded on all sides by mountain peaks. And those vineyards aren’t just for show — you’ll have the opportunity to taste wines from Seeleiten’s own winery.

Conti di San Bonifacio is a beautifully renovated seven-room farmhouse on a hill in Tuscany, surrounded by several hundred acres of vineyards, olive groves and rolling woods. Naturally, the food is a major part of the appeal. The wine and olive oil made here have a following far beyond the hotel’s walls, and many of the ingredients for the meals are grown on the property.

At Castello Banfi il Borgo, the 14-room boutique is only the keep to this Tuscan castle-on-a-hill — the castello is the headquarters of the working wine estate, while the borgo is the boutique hotel that’s been fashioned from the adjoining village buildings. Thankfully, there’s also the small matter of a seven-thousand-acre vineyard, sloping gently down from the fortress to meet the surrounding valley.

Les Sources de Caudalie, on the grounds of the Château Smith Haut-Lafitte vineyard, is at first glance just a delightful countryside retreat — sixty-one contemporary luxury hotel rooms in an idyllic setting complete with phenomenal French country cooking and some of the world’s finest wines. As luck would have it, though, this vineyard is now an exemplary organic operation that happens to have a natural thermal spring beneath it.

Hôtel & Restaurant Lalique – Château Lafaurie Peyraguey is a collaboration between Lalique, the venerable glassmaker, and Lafaurie-Peyraguey, the Sauternes winery. With just thirteen suites, it’s modestly sized, but in terms of luxury, its ambitions are sky-high. This is, after all, the first premier cru winery to open its doors to overnight guests, and it’s got 400 years of history to live up to.

This castle dates back to the 1700s, which explains its unusual Italianate style, and only became a hotel in 2017, after three centuries as a private estate. Its setting, just to the north of Aix-en-Provence, endears it to wine lovers, as does the Fonscolombe winery itself, which produces organic reds, whites, and rosés. But the key to its appeal is that it’s quite simply the most luxurious hotel around.

Hotel Peralada Wine Spa & Golf is just what it says it is: a luxury hotel in the Empordà, between Girona and the French border, featuring a working winery and associated vineyards, a luxurious wine-focused spa, and one of the top golf courses on the Costa Brava. And the name leaves out several features, including a casino, a preserved Carmelite convent, and a generous handful of dining and drinking venues.

In the mountains outside the city of Tarragona, is the spectacular Montsant National Park. And in the 12th century, in the foothills to these mountains, a group of Carthusian monks established a monastery and a farm, growing grapes, olives, and other fruits. It’s today’s hotel guests who reap the benefits, as the old monastery, now thoroughly updated, is open to travelers in the form of Terra Dominicata – Hotel & Winery.

There’s an architecture arms race afoot in the Rioja wine country, with buildings by the likes of Zaha Hadid and Santiago Calatrava now joined by one from the Basque country’s adopted son, Frank Gehry. Originally intended just as a corporate headquarters for the Marquès de Riscal, the building proved to be too special not to share — so now it’s open to the paying public, as one of the most unique winery hotels in the world.

Increasingly we’ve seen stylish country inns popping up in Portugal to rival those in Italy, but L’AND Vineyards represents something in another league entirely — a striking work of modern hotel architecture on par with some of the world’s recent best, with a winery, a fine restaurant and a set of high-design suites with retractable roofs thrown in for good measure.

Quinta da Pacheca Wine House Hotel is an 18th-century manor house on a working Douro Valley winery that combines classic charm with contemporary interior design and up-to-date boutique-era comforts. Along with traditional hotel rooms you’ll find two rows of pod-like cabins made from decommissioned wine barrels, just big enough for a cozy bedroom and bathroom and an outdoor terrace overlooking the vineyards.

São Lourenço do Barrocal is a 200-year-old, 2,000-acre agricultural estate in Portugal’s spectacular Alentejo countryside. Today, the estate is still an organic farm, producing wine, fruits, and other foodstuffs, but much of its infrastructure has been put to new use as a tranquil and quietly stylish luxury boutique hotel — barns, outbuildings, even an olive press have been transformed for use as hotel rooms, suites, cottages, and a spa.